Cancer drugs that halt tumors can also shrink them

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Posted On: August 23, 2017 by Essentially Women in: Essential News

A class of drugs known as CDK4/6 inhibitors, which have been approved for treating some types of breast cancer, may have much more to offer than previously thought. Not only can they stop tumors from growing by halting cell division, but they can also "spur the immune system to attack and shrink" them. This was the main finding of a new study from the Dana-Farber Cancer Institute and Brigham and Women's Hospital, both in Boston, MA, the results of which have been published in the journal Nature. CDK4/6 inhibitors are a class of drugs that work by blocking certain proteins called cyclin-dependent kinases (CDKs) 4 and 6, which promote the growth of cancer cells. At present, these drugs have only been approved for treating some patients with metastatic breast cancer, "but they've also shown promise against others types of tumors in clinical trials," says co-first author Shom Goel, Ph.D., of the Dana-Farber Cancer Institute. In the United States, around 1 in 8 women

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