Alcohol Consumption, Cigarette Smoking, and Familial Breast Cancer Risk

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A recent study from Medscape has found that alcohol consumption and cigarette smoking are associated with an increased risk of breast cancer (BC), but it is unclear whether these associations vary by a woman's familial BC risk. 

The conclusion found was that moderate alcohol intake was associated with increased BC risk, particularly for women with ER-positive BC, but only for those at lower predicted familial BC risk (5-year BOADICEA < 1.25). For women with a high FRP (5-year BOADICEA ≥ 6.5%) who also consumed alcohol, being a current smoker was associated with increased BC risk. 

These findings can have implications in terms of absolute risk reduction, as alcohol and smoking are modifiable risk factors and present risk reduction opportunities for women across the spectrum of familial risk. 

Click here to read the full study from Medscape

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