Unhealthy Gut Microbiome May Make Breast Cancers More Aggressive Finds Study

Home Blog Unhealthy Gut Microbiome May Make Breast Cancers More Aggressive Finds Study

A newly released study from the University of Virginia Cancer Center connects an unhealthy gut microbiome with breast cancer that can become invasive and spread to other organs faster. The study, funded by a Susan G. Komen grant, found that if the gut microbiome or the microbial contents of the gut of the lab mice are altered, their hormone-receptor-positive breast cancer turned more aggressive. When the nature of the normal bacteria in the gut was changed, it changed the nature of the cancer and then primed it to spread to other organs. 

It was previously unknown why some of the hormone-receptor-positive cancers are more aggressive and invasive compared to others. 

People with an unhealthy gut microbiome have an increased inflammation of the gut. Disrupting the gut microbiome resulted in long-term inflammation within the tissue and the tumor environment. Research suggests that having an unhealthy microbiome and the associated changes within the microbiome can be early predictors of invasive or metastatic breast cancer.

Research was conducted on lab mice and may not be the same in humans. In addition, the study should not be construed to cause women with breast cancer to steer away from antibiotics.  

Read the full story from News Medical.

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